CRISPR-Display

CRISPR-Display

CRISPR-Display is a versatile method for ectopically localizing ncRNA domains or ribonucleoprotein (RNP) complexes to any genomic locus, where their functions can be scrutinized or utilized (pictured on the left). CRISPR-Display can reconstitute both natural regulatory ncRNAs and artificial ncRNA devices, and can simultaneously deploy multiple different functions to discrete genomic targets. This enables an extremely broad range of bioengineering, systems-biological, and chemical-biological applications.

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